N7-platinated ribonucleotides are not incorporated by RNA polymerases. New perspectives for a rational design of platinum antitumor drugs
Author:
Funder
University of Salento
Consorzio Interuniversitario di Ricerca in Chimica dei Metalli nei Sistemi Biologici
Publisher
Elsevier BV
Subject
Inorganic Chemistry,Biochemistry
Reference34 articles.
1. Platinum Compounds: a New Class of Potent Antitumour Agents
2. Interactions of Cisplatin with non-DNA Targets and their Influence on Anticancer Activity and Drug Toxicity: The Complex World of the Platinum Complex
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1. Compatibility of Nucleobases Containing Pt(II) Complexes with Red Blood Cells for Possible Drug Delivery Applications;Molecules;2023-09-22
2. Incorporation of N7-Platinated Guanines into Thermus Aquaticus (Taq) DNA Polymerase: Atomistic Insights from Molecular Dynamics Simulations;International Journal of Molecular Sciences;2023-06-07
3. Platinum-Nucleos(t)ide Compounds as Possible Antimetabolites for Antitumor/Antiviral Therapy: Properties and Perspectives;Pharmaceutics;2023-03-14
4. Synthesis and comparative evaluation of the cytotoxic activity of cationic organometallic complexes of the type [Pt(η1-CH2-CH2-OR)(DMSO)(phen)]+ (R = Me, Et, Pr, Bu);Inorganica Chimica Acta;2023-02
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