Are drug holidays a safe option in treatment of osteoporosis? — Insights from an in silico mechanistic PK–PD model of denosumab treatment of postmenopausal osteoporosis-Reference-Cited by-同舟云学术

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Are drug holidays a safe option in treatment of osteoporosis? — Insights from an in silico mechanistic PK–PD model of denosumab treatment of postmenopausal osteoporosis

Published:2021-01 Issue: Volume:113 Page:104140
ISSN:1751-6161
Container-title:Journal of the Mechanical Behavior of Biomedical Materials
language:en
Short-container-title:Journal of the Mechanical Behavior of Biomedical Materials

Author:

Martínez-Reina Javier,Calvo-Gallego José Luis,Pivonka Peter

Funder

Ministerio de Ciencia e Innovación

Publisher

Elsevier BV

Subject

Mechanics of Materials,Biomedical Engineering,Biomaterials

Reference40 articles.

1. Drug holidays from bisphosphonates and denosumab in postmenopausal osteoporosis: EMAS position statement;Anagnostis;Maturitas,2017

2. Bone mineralization: from tissue to crystal in normal and pathological contexts;Bala;Osteoporos Int.,2013

3. Effects of denosumab treatment and discontinuation on bone mineral density and bone turnover markers in postmenopausal women with low bone mass;Bone;J. Clin. Endocrinol. Metabol.,2011

4. Damage type and strain mode associations in human compact bone bending fatigue;Boyce;J. Orthopaed. Res.,1998

5. Effects and management of denosumab discontinuation;Chapurlat;Joint Bone Spine,2018

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