Glucokinase activation–a strategy for T2D therapy: recent developments

Author:

Sarabu Ramakanth,Taub Rebecca,Grimsby Joseph

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Molecular Medicine

Reference21 articles.

1. Targeting glucokinase activation for the treatment of type 2 diabetes – a status review;Sarabu;Curr. Opin. Drug Discov. Dev.,2005

2. Glucokinase: old enzyme, new target;Kietzmann;Expert Opin. Ther. Patents,2005

3. A protein from rat liver confers to glucokinase the property of antagonistically regulated by fructose-6-phosphate and fructose-1-phosphate;Van Schaftingen;Eur. J. Biochem.,1989

4. Evidence for a role of glucose induced translocation of glucokinase in the control of hepatic glycogen synthesis;Agius;J. Biol. Chem.,1996

5. Glucokinase (GCK) mutations in hyper- and hypoglycemia: maturity-onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemia of infancy;Gloyn;Hum. Mutat.,2002

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