Deferasirox selectively induces cell death in the clinically relevant population of leukemic CD34+CD38– cells through iron chelation, induction of ROS, and inhibition of HIF1α expression-Reference-Cited by-同舟云学术

Deferasirox selectively induces cell death in the clinically relevant population of leukemic CD34+CD38– cells through iron chelation, induction of ROS, and inhibition of HIF1α expression

Published:2019-02 Issue: Volume:70 Page:55-69.e4
ISSN:0301-472X
Container-title:Experimental Hematology
language:en
Short-container-title:Experimental Hematology

Author:

Shapira Saar,Raanani Pia,Samara Aladin,Nagler Arnon,Lubin Ido,Arber Nadir,Granot Galit^ORCID

Publisher

Elsevier BV

Subject

Cancer Research,Cell Biology,Genetics,Hematology,Molecular Biology

Reference65 articles.

1. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell;Bonnet;Nat Med,1997

3. Anthracycline dose intensification in acute myeloid leukemia;Fernandez;N Engl J Med,2009

4. Attempts to optimize induction and consolidation treatment in acute myeloid leukemia: results of the MRC AML12 trial;Burnett;J Clin Oncol,2010

5. An update of current treatments for adult acute myeloid leukemia;Dombret;Blood,2016

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