A fluorescent splice-switching mouse model enables high-throughput, sensitive quantification of antisense oligonucleotide delivery and activity

Author:

Byrnes Amy E.ORCID,Roudnicky Filip,Gogineni Alvin,Soung Allison L.,Xiong Monica,Hayne Margaret,Heaster-Ford Tiffany,Shatz-Binder Whitney,Dominguez Sara L.,Imperio Jose,Gierke Sarah,Roberts Jasmine,Guo Jinglong,Ghosh Soumitra,Yu Charles,Roose-Girma Merone,Elstrott Justin,Easton Amy,Hoogenraad Casper C.ORCID

Publisher

Elsevier BV

Reference46 articles.

1. The chemical evolution of oligonucleotide therapies of clinical utility;Khvorova;Nat. Biotechnol.,2017

2. RNA-Targeted Therapeutics;Crooke;Cell Metabol.,2018

3. Antisense Oligonucleotides: Translation from Mouse Models to Human Neurodegenerative Diseases;Schoch;Neuron,2017

4. Antisense Oligonucleotides: An Emerging Area in Drug Discovery and Development;Dhuri;J. Clin. Med.,2020

5. Antisense oligonucleotides: modifications and clinical trials;Sharma;MedChemComm,2014

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