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Arrest of B Lymphocyte Terminal Differentiation by CD40 Signaling: Mechanism for Lack of Antibody-Secreting Cells in Germinal Centers

  • Published:1998-06 Issue:6 Volume:8 Page:733-742
  • ISSN:1074-7613
  • Container-title:Immunity
  • language:en
  • Short-container-title:Immunity

Author:

Randall Troy D,Heath Andrew W,Santos-Argumedo Leopoldo,Howard Maureen C,Weissman Irving L,Lund Frances E

Publisher

Elsevier BV

Subject

Infectious Diseases,Immunology,Immunology and Allergy

Reference47 articles.

1. Molecular and biological characterization of a murine ligand for CD40;Armitage;Nature,1992

2. Human B cell proliferation and Ig secretion induced by recombinant CD40 ligand are modulated by soluble cytokines;Armitage;J. Immunol,1993

3. Generation of memory B cells and plasma cells in vitro;Arpin;Science,1995

4. Memory B cells are biased towards terminal differentiation;Arpin;J. Exp. Med,1997

5. The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome;Aruffo;Cell,1993
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