Locus coeruleus MRI contrast is reduced in Alzheimer's disease dementia and correlates with CSF Aβ levels

Author:

Betts Matthew J.12,Cardenas‐Blanco Arturo12,Kanowski Martin3,Spottke Annika4,Teipel Stefan J.56,Kilimann Ingo5,Jessen Frank47,Düzel Emrah128

Affiliation:

1. German Center for Neurodegenerative Diseases (DZNE)MagdeburgGermany

2. Institute of Cognitive Neurology and Dementia Research, Otto‐von‐Guericke‐University MagdeburgMagdeburgGermany

3. Department of NeurologyUniversity Hospital of Magdeburg, Otto‐von‐Guericke‐University MagdeburgMagdeburgGermany

4. German Center for Neurodegenerative Diseases (DZNE)BonnGermany

5. German Center for Neurodegenerative Diseases (DZNE)RostockGermany

6. Department of Psychosomatic MedicineUniversity Medicine RostockRostockGermany

7. Department of PsychiatryUniversity of CologneCologneGermany

8. Institute of Cognitive Neuroscience, University College LondonLondonUK

Funder

German Center for Neurodegenerative Diseases

Publisher

Wiley

Subject

Psychiatry and Mental health,Neurology (clinical)

Reference16 articles.

1. Stages of the Pathologic Process in Alzheimer Disease: Age Categories From 1 to 100 Years

2. Neuromelanin magnetic resonance imaging of locus ceruleus and substantia nigra in Parkinson's disease

3. In vivo mapping of the human locus coeruleus

4. D.V.Clewett T.‐H.Lee S.Greening A.Ponzio E.Margalit M.Mather.Neuromelanin marks the spot: identifying a locus coeruleus biomarker of cognitive reserve in healthy aging.Neurobiol Aging 201510.1016/j.neurobiolaging.2015.09.019

5. In vivo MRI assessment of the human locus coeruleus along its rostrocaudal extent in young and older adults

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