Why there are so many contradicted or exaggerated findings in highly-cited clinical research?

Author:

Lu Mengyi,Liu Suyu,Yuan Ying

Funder

National Cancer Institute

Publisher

Elsevier BV

Subject

Pharmacology (medical),General Medicine

Reference23 articles.

1. Comparison of observational studies and randomized, controlled trials;Benson;N. Engl. J. Med.,2000

2. Could Fisher, Jeffreys and Neyman have agreed upon testing?;Berger;Stat. Sci.,2003

3. Testing precise hypotheses;Berger;Stat. Sci.,1987

4. Testing a point null hypothesis: the irreconcilability of p value and evidence;Berger;J. Am. Stat. Assoc.,1987

5. Large trials vs meta-analysis of smaller trials: how do their results compare?;Cappelleri;J. Am. Med. Assoc.,1996

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