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Adaptive design of confirmatory trials: Advances and challenges

  • Published:2015-11 Issue: Volume:45 Page:93-102
  • ISSN:1551-7144
  • Container-title:Contemporary Clinical Trials
  • language:en
  • Short-container-title:Contemporary Clinical Trials

Author:

Lai Tze Leung,Lavori Philip W.,Tsang Ka Wai

Funder

NSF

NIH

National Center for Research Resources

National Institutes of Health

Publisher

Elsevier BV

Subject

Pharmacology (medical),General Medicine

Reference72 articles.

1. Multistage testing with adaptive designs (with discussion);Bauer;Biomed. Inform. Med. Biol.,1989

2. The role of internal pilots in increasing the efficiency of clinical trials;Wittes;Stat. Med.,1990

3. A two-sample test for a linear hypothesis whose power is independent of the variance;Stein;Ann. Math. Stat.,1945

4. Sample size re-estimation without unblinding for normally distributed outcomes with unknown variance;Gould;Comm. Stat. Ser. A,1992

5. The use of interim analysis in sample size adjustment;Herson;Drug Inf. J.,1993

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