Inefficiency of two-stage designs in phase II oncology clinical trials with high proportion of inevaluable patients

Author:

Ji Lingyun,Whangbo Jennifer,Levine John E.,Alonzo Todd A.

Publisher

Elsevier BV

Subject

Pharmacology (medical),General Medicine

Reference33 articles.

1. Optimal two-stage designs for phase II clinical trials;Simon;Control. Clin. Trials,1989

2. Sample size tables for exact single-stage phase II designs;A’Hern;Stat. Med.,2001

3. Modified Simon’s minimax and optimal two-stage designs for single-arm phase II cancer clinical trials;Kim;Oncotarget,2019

4. Considerations for designing and implementing phase II oncology clinical trials;Wei;Biostat. Biom. Open Access J.,2019

5. Adaptive designs in clinical trials: why use them, and how to run and report them;Pallmann;BMC Med.,2018

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