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Single-molecule imaging revealed dynamic GPCR dimerization

Published:2014-04 Issue: Volume:27 Page:78-86
ISSN:0955-0674
Container-title:Current Opinion in Cell Biology
language:en
Short-container-title:Current Opinion in Cell Biology

Author:

Kasai Rinshi S,Kusumi Akihiro

Funder

Japan Society for Promotion of Science

Ministry of Education, Culture, Sports, Science and Technology (MEXT) of Japan

World Premiere Research Center Initiative of the MEXT

Publisher

Elsevier BV

Subject

Cell Biology

Reference49 articles.

1. Coexpression studies with mutant muscarinic/adrenergic receptors provide evidence for intermolecular cross-talk between G-protein-linked receptors;Maggio;Proc Natl Acad Sci U S A,1993

2. Emerging role of homo- and heterodimerization in G-protein-coupled receptor biosynthesis and maturation;Bulenger;Trends Pharmacol Sci,2005

3. The apparent cooperativity of some GPCRs does not necessarily imply dimerization;Chabre;Trends Pharmacol Sci,2009

4. High-resolution crystal structure of an engineered human β2-adrenergic G protein-coupled receptor;Cherezov;Science,2007

5. A specific cholesterol binding site is established by the 2.8Å structure of the human β2-adrenergic receptor;Hanson;Structure,2008

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