(9-[4-acetyl-3-hydroxy-2-n-propylphenoxy) methyl]-3-(1H-tetrazol-5-yl)-4H-pyrido [1, 2-a] pyrimidin-4-one), AS-35, inhibits leukotriene synthesis

Author:

Hamasaki Yuhei,Zaitu Masafumi,Tsuji Kosuke,Miyazaki Michiko,Hayasaki Rika,Muro Eriko,Yamamoto Shuichi,Kobayashi Ikuko,Matsuo Muneaki,Ichimaru Tomohiro,Miyazaki Sumio

Publisher

Elsevier BV

Subject

Pharmacology,Immunology

Reference22 articles.

1. Peptide leukotriene antagonistic activity of AS-35, a new antiallergic drug;Kasai;Jpn J. Pharmacol.,1992

2. Inhibition of radiolabeled leukotriene-binding by AS-35 in guinea pig lung membrane fraction;Kasai;Jpn J. Pharmacol.,1992

3. Inhibitory effect of AS-35, A novel antiallergic drug, on chemical mediator release from human eosinophil;Kawashima;Alerugi (English Abst),1994

4. Immunopharmacological studies on AS-35, an unique antiallergic drug. (1) Antagonistic actions upon leukotriene (LT) and inhibitory effects on chemical mediator release;Kawashima;N. Engl. Regional Allergy Pro.,1988

5. Effect of AS-35 on agonist-induced contractions and the resting tonus of airway smooth muscles and the in vitro release of chemical mediators from passively sensitized lung fragments from humans and guinea pigs;Watanabe-Kohno;Jpn J. Pharmacol.,1992

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