Paralog-divergent Features May Help Reduce Off-target Effects of Drugs: Hints from Glucagon Subfamily Analysis-Reference-Cited by-同舟云学术

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Paralog-divergent Features May Help Reduce Off-target Effects of Drugs: Hints from Glucagon Subfamily Analysis

Published:2017-08 Issue:4 Volume:15 Page:246-254
ISSN:1672-0229
Container-title:Genomics, Proteomics & Bioinformatics
language:en
Short-container-title:Genomics, Proteomics & Bioinformatics

Author:

Sa Zhining,Zhou Jingqi,Zou Yangyun,Su Zhixi,Gu Xun

Funder

National Natural Science Foundation of China

Fudan University

Iowa State University

Publisher

Elsevier BV

Subject

Computational Mathematics,Genetics,Molecular Biology,Biochemistry

Reference47 articles.

1. Five critical elements to ensure the precision medicine;Chen;Cancer Metastasis Rev,2015

2. Is there a case for selectively promiscuous anticancer drugs?;Fernández;Drug Discov Today,2009

3. Turning promiscuous kinase inhibitors into safer drugs;Zhang;Trends Biotechnol,2008

4. Statistical methods for testing functional divergence after gene duplication;Gu;Mol Biol Evol,1999

5. Present and future of pathway analysis in drug discovery;Yuryev,2008

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3. Antisense Inhibition of Glucagon Receptor by IONIS-GCGRRx Improves Type 2 Diabetes Without Increase in Hepatic Glycogen Content in Patients With Type 2 Diabetes on Stable Metformin Therapy;Diabetes Care;2019-02-14

4. Covalent Inhibition in Drug Discovery: Filling the Void in Literature;Current Topics in Medicinal Chemistry;2018-10-04

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