Relevance of desorption kinetics and permeability for in vitro-based predictions of hepatic clearance in fish

Author:

Krause SophiaORCID,Goss Kai-Uwe

Funder

Umweltbundesamt

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Aquatic Science

Reference47 articles.

1. Simultaneous exposure of fish to endosulfan and disulfoton in vivo: ultrastructural, stereological and biochemical reactions in hepatocytes of male rainbow trout (Oncorhynchus mykiss);Arnold;Aquatic Toxicology,1995

2. Physicochemical Profiling (Solubility, Permeability and Charge State);Avdeef;Current Topics in Medicinal Chemistry,2001

3. The rise of PAMPA;Avdeef;Expert Opinion on Drug Metabolism & Toxicology,2005

4. Absorption and drug development: solubility, permeability, and charge state;Avdeef,2012

5. Determination of hepatic clearance with the account of drug-protein binding kinetics;Berezhkovskiy;Journal of Pharmaceutical Sciences,2012

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