Safety and immunogenicity of an inactivated recombinant Newcastle disease virus vaccine expressing SARS-CoV-2 spike: Interim results of a randomised, placebo-controlled, phase 1 trial

Author:

Pitisuttithum Punnee,Luvira Viravarn,Lawpoolsri Saranath,Muangnoicharoen Sant,Kamolratanakul Supitcha,Sivakorn Chaisith,Narakorn Piengthong,Surichan Somchaiya,Prangpratanporn Sumalee,Puksuriwong Suttida,Lamola Steven,Mercer Laina D.ORCID,Raghunandan Rama,Sun WeinaORCID,Liu Yonghong,Carreño Juan Manuel,Scharf Rami,Phumratanaprapin Weerapong,Amanat Fatima,Gagnon Luc,Hsieh Ching-Lin,Kaweepornpoj Ruangchai,Khan Sarwat,Lal Manjari,McCroskery Stephen,McLellan Jason,Mena Ignacio,Meseck Marcia,Phonrat Benjaluck,Sabmee Yupa,Singchareon Ratsamikorn,Slamanig Stefan,Suthepakul Nava,Tcheou JohnstoneORCID,Thantamnu Narumon,Theerasurakarn Sompone,Tran Steven,Vilasmongkolchai Thanakrit,White Jessica A,Bhardwaj Nina,Garcia-Sastre Adolfo,Palese Peter,Krammer Florian,Poopipatpol Kittisak,Wirachwong Ponthip,Hjorth Richard,Innis Bruce LORCID

Publisher

Elsevier BV

Subject

General Medicine

Reference21 articles.

1. (WHO) WHO. https://www.who.int/director-general/speeches/detail/director-general-s-opening-remarks-at-the-media-briefing-on-covid-19-9-april-2021. 2021.

2. Global production capacity of seasonal and pandemic influenza vaccines in 2019;Sparrow;Vaccine,2021

3. A Newcastle disease virus (NDV) expressing a membrane-anchored spike as a cost-effective inactivated SARS-CoV-2 vaccine;Sun;Vaccines (Basel),2020

4. Structure-based design of prefusion-stabilized SARS-CoV-2 spikes;Hsieh;Science,2020

5. A Newcastle disease virus- expressing a stabilized spike protein of SARS-CoV-2 induces protective immune responses;Sun;Nat Commun,2021

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