Safety and immunogenicity of a SARS-CoV-2 recombinant protein nanoparticle vaccine (GBP510) adjuvanted with AS03: A randomised, placebo-controlled, observer-blinded phase 1/2 trial

Author:

Song Joon YoungORCID,Choi Won Suk,Heo Jung Yeon,Lee Jin Soo,Jung Dong Sik,Kim Shin-Woo,Park Kyung-Hwa,Eom Joong Sik,Jeong Su Jin,Lee Jacob,Kwon Ki Tae,Choi Hee Jung,Sohn Jang Wook,Kim Young KeunORCID,Noh Ji Yun,Kim Woo Joo,Roman François,Ceregido Maria Angeles,Solmi Francesca,Philippot Agathe,Walls Alexandra C.,Carter Lauren,Veesler DavidORCID,King Neil P.,Kim Hun,Ryu Ji Hwa,Lee Su JeenORCID,Park Yong Wook,Park Ho Keun,Cheong Hee Jin

Publisher

Elsevier BV

Subject

General Medicine

Reference24 articles.

1. World Health Organization. Coronavirus disease 2019 (COVID-19): situation report. Available at: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/situation-reports. Accessed 31 January 2022.

2. Scientific rationale for developing potent RBD-based vaccines targeting COVID-19;Kleanthous;NPJ Vaccines,2021

3. Elicitation of potent neutralizing antibody responses by designed protein nanoparticle vaccines for SARS-CoV-2;Walls;Cell,2020

4. Mapping neutralizing and immunodominant sites on the SARS-CoV-2 spike receptor-binding domain by structure-guided high-resolution serology;Piccoli;Cell,2020

5. Structure, function, and antigenicity of the SARS-CoV-2 spike glycoprotein;Walls;Cell,2020

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