Experience with a Placebo-Controlled Randomized Clinical Trial of a Disease-Modifying Drug for Osteoarthritis: The Doxycycline Trial

Author:

Brandt Kenneth D.,Mazzuca Steven A.

Publisher

Elsevier BV

Subject

Rheumatology

Reference55 articles.

1. Non-surgical treatment of osteoarthritis: a half century of “advances”;Brandt;Ann Rheum Dis,2004

2. Finding clinical endpoints and biosurrogates in preclinical knee osteoarthritis;De Pablo;J Rheumatol,2005

3. Which is the best radiologic/radiographic protocol for a clinical trial of a structure-modifying drug in patients with knee osteoarthritis? Proceedings of January 17–18, 2002 Workshop in Toussus-le-Noble, France;Brandt;J Rheumatol,2002

4. Effect of doxycycline on progression of osteoarthritis;Brandt;Arthritis Rheum,2005

5. Doxycycline inhibits type XI collagenolytic activity of extracts from human osteoarthritic cartilage and of gelatinase;Yu;J Rheumatol,1991

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