A Phosphomimetic Mutation Stabilizes SOD1 and Rescues Cell Viability in the Context of an ALS-Associated Mutation-Reference-Cited by-同舟云学术

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A Phosphomimetic Mutation Stabilizes SOD1 and Rescues Cell Viability in the Context of an ALS-Associated Mutation

Published:2016-11 Issue:11 Volume:24 Page:1898-1906
ISSN:0969-2126
Container-title:Structure
language:en
Short-container-title:Structure

Author:

Fay James M.,Zhu Cheng,Proctor Elizabeth A.,Tao Yazhong,Cui Wenjun,Ke Hengming,Dokholyan Nikolay V.

Funder

NIH

National Institute on Aging

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference64 articles.

1. ALSoD: a user-friendly online bioinformatics tool for amyotrophic lateral sclerosis genetics;Abel;Hum. Mutat.,2012

2. Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease;Augustinack;Acta Neuropathol.,2002

3. Oxidative stress in ALS: key role in motor neuron injury and therapeutic target;Barber;Free Radic. Biol. Med.,2010

4. Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target;Barber;Biochim. Biophys. Acta,2006

5. ALS: a disease of motor neurons and their nonneuronal neighbors;Boillee;Neuron,2006

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3. Unveiling the double-edged sword: SOD1 trimers possess tissue-selective toxicity and bind septin-7 in motor neuron-like cells;Structure;2024-08

4. The Ile35 Residue of the ALS-Associated Mutant SOD1 Plays a Crucial Role in the Intracellular Aggregation of the Molecule;Molecular Neurobiology;2024-07-26

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