Why an A-Loop Phospho-Mimetic Fails to Activate PAK1: Understanding an Inaccessible Kinase State by Molecular Dynamics Simulations-Reference-Cited by-同舟云学术

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Why an A-Loop Phospho-Mimetic Fails to Activate PAK1: Understanding an Inaccessible Kinase State by Molecular Dynamics Simulations

Published:2010-07 Issue:7 Volume:18 Page:879-890
ISSN:0969-2126
Container-title:Structure
language:en
Short-container-title:Structure

Author:

Ng Yuen-Wai,Raghunathan Devanathan,Chan Perry M.,Baskaran Yohendran,Smith Derek J.,Lee Chung-Hung,Verma Chandra,Manser Ed

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference83 articles.

1. Activation loop phosphorylation and catalysis in protein kinases: is there functional evidence for the autoinhibitor model?;Adams;Biochemistry,2003

2. Serine-53 at the tip of the glycine-rich loop of cAMP-dependent protein kinase: role in catalysis, P-site specificity, and interaction with inhibitors;Aimes;Biochemistry,2000

3. p21-activated kinase regulates mast cell degranulation via effects on calcium mobilization and cytoskeletal dynamics;Allen;Blood,2009

4. A tale of two Paks;Arias-Romero;Biol. Cell,2008

5. Regulation of hippocampal long-term potentiation by p21-activated protein kinase 1 (PAK1);Asrar;Neuropharmacology,2009

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5. Activation of p53: How phosphorylated Ser15 triggers sequential phosphorylation of p53 at Thr18 by CK1δ;Proteins: Structure, Function, and Bioinformatics;2022-07-14

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