The Cdc48 N-terminal domain has a molecular switch that mediates the Npl4-Ufd1-Cdc48 complex formation

Author:

Oppenheim Tal,Radzinski Meytal,Braitbard Merav,Brielle Esther S.,Yogev Ohad,Goldberger Eliya,Yesharim Yarden,Ravid Tommer,Schneidman-Duhovny Dina,Reichmann DanaORCID

Funder

Azrieli Foundation

United States - Israel Binational Science Foundation

Ministry of Science and Technology, Israel

Human Frontier Science Program

Israel Ministry of Innovation Science & Technology

United States-Israel Binational Science Foundation

Israel Science Foundation

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference108 articles.

1. The Cdc48 machine in endoplasmic reticulum associated protein degradation;Wolf;Biochim. Biophys. Acta,2012

2. A stress-responsive system for mitochondrial protein degradation;Heo;Mol. Cell,2010

3. Chromatin-associated degradation is defined by UBXN-3/FAF1 to safeguard DNA replication fork progression;Franz;Nat. Commun.,2016

4. Cdc48/VCP promotes chromosome morphogenesis by releasing condensin from self-entrapment in chromatin;Thattikota;Mol. Cell,2018

5. The requirement for Cdc48/p97 in nuclear protein quality control degradation depends on the substrate and correlates with substrate insolubility;Gallagher;J. Cell Sci.,2014

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