ATP-site inhibitors induce unique conformations of the acute myeloid leukemia-associated Src-family kinase, Fgr-Reference-Cited by-同舟云学术

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ATP-site inhibitors induce unique conformations of the acute myeloid leukemia-associated Src-family kinase, Fgr

Published:2022-11 Issue:11 Volume:30 Page:1508-1517.e3
ISSN:0969-2126
Container-title:Structure
language:en
Short-container-title:Structure

Author:

Du Shoucheng,Alvarado John J.,Wales Thomas E.,Moroco Jamie A.,Engen John R.,Smithgall Thomas E.^ORCID

Funder

Argonne National Laboratory

National Institutes of Health

U.S. Department of Energy

National Cancer Institute

National Institute of General Medical Sciences

Office of Science

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference37 articles.

1. Gain-of-function mutations in a member of the Src family kinases cause autoinflammatory bone disease in mice and humans;Abe;Proc. Natl. Acad. Sci. USA,2019

2. PHENIX: a comprehensive Python-based system for macromolecular structure solution;Adams;Acta Crystallogr. D Biol. Crystallogr.,2010

3. Pyrrolo[2, 3-d]pyrimidines containing an extended 5-substituent as potent and selective inhibitors of lck I;Arnold;Bioorg. Med. Chem. Lett.,2000

4. Targeting dynamic ATP-binding site features allows discrimination between highly homologous protein kinases;Chakraborty;ACS Chem. Biol.,2019

5. Endogenous and synthetic inhibitors of the Src-family protein tyrosine kinases;Chong;Biochim. Biophys. Acta,2005

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