2,5-Pyridinedicarboxylic acid is a bioactive and highly selective inhibitor of D-dopachrome tautomerase-Reference-Cited by-同舟云学术

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2,5-Pyridinedicarboxylic acid is a bioactive and highly selective inhibitor of D-dopachrome tautomerase

Published:2023-03 Issue:3 Volume:31 Page:355-367.e4
ISSN:0969-2126
Container-title:Structure
language:en
Short-container-title:Structure

Author:

Parkins Andrew,Das Pragnya,Prahaladan Varsha,Rangel Vanessa M.,Xue Liang,Sankaran Banumathi,Bhandari Vineet,Pantouris Georgios^ORCID

Funder

Howard Hughes Medical Institute

National Institute of General Medical Sciences

National Science Foundation

Office of Science

University of the Pacific

National Institutes of Health

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference66 articles.

1. The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF);Merk;Proc. Natl. Acad. Sci. USA,2011

2. MIF signal transduction initiated by binding to CD74;Leng;J. Exp. Med.,2003

3. The immunoregulatory mediator macrophage migration inhibitory factor (MIF) catalyzes a tautomerization reaction;Rosengren;Mol. Med.,1996

4. Molecular cloning of human D-dopachrome tautomerase cDNA: N-terminal proline is essential for enzyme activation;Nishihira;Biochem. Biophys. Res. Commun.,1998

5. 4-Iodopyrimidine labeling reveals nuclear translocation and nuclease activity for both MIF and MIF2;Xiao;Chemistry,2022

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The synthesis of 1,2,3-triazoles as binders of D-dopachrome tautomerase (D-DT) for the development of dual-targeting inhibitors;European Journal of Medicinal Chemistry;2024-10

2. Host derived macrophage migration inhibitory factor expression attenuates anti-tumoral immune cell accumulation and promotes immunosuppression in the tumor microenvironment of head and neck squamous cell carcinoma;Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease;2024-10

3. The C-terminal Region of D-DT Regulates Molecular Recognition for Protein–Ligand Complexes;Journal of Medicinal Chemistry;2024-04-26

4. Iguratimod, an allosteric inhibitor of macrophage migration inhibitory factor (MIF), prevents mortality and oxidative stress in a murine model of acetaminophen overdose;Molecular Medicine;2024-03-27

5. Protocol for purification and enzymatic characterization of members of the human macrophage migration inhibitory factor superfamily;STAR Protocols;2023-09

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