A two-site flexible clamp mechanism for RET-GDNF-GFRα1 assembly reveals both conformational adaptation and strict geometric spacing-Reference-Cited by-同舟云学术

A two-site flexible clamp mechanism for RET-GDNF-GFRα1 assembly reveals both conformational adaptation and strict geometric spacing

Published:2021-01 Issue: Volume: Page:
ISSN:0969-2126
Container-title:Structure
language:en
Short-container-title:Structure

Author:

Adams Sarah E.^ORCID,Purkiss Andrew G.,Knowles Phillip P.,Nans Andrea,Briggs David C.,Borg Annabel,Earl Christopher P.^ORCID,Goodman Kerry M.,Nawrotek Agata,Borg Aaron J.,McIntosh Pauline B.,Houghton Francesca M.^ORCID,Kjær Svend,McDonald Neil Q.

Funder

Medical Research Council

Cancer Research UK

Wellcome Trust

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference84 articles.

1. ICM—a new method for protein modeling and design: applications to docking and structure prediction from the distorted native conformation;Abagyan;J. Comput. Chem.,1994

2. PHENIX: a comprehensive Python-based system for macromolecular structure solution;Adams;Acta Crystallogr. D Biol. Crystallogr.,2010

3. Towards automated crystallographic structure refinement with phenix.refine;Afonine;Acta Crystallogr. D Biol. Crystallogr.,2012

4. Real-space refinement in PHENIX for cryo-EM and crystallography;Afonine;Acta Crystallogr. D Struct. Biol.,2018

5. Privateer: software for the conformational validation of carbohydrate structures;Agirre;Nat. Struct. Mol. Biol.,2015

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Architecture and regulation of a GDNF-GFRα1 synaptic adhesion assembly;Nature Communications;2023-11-20

2. Receptor Tyrosine Kinases and Their Ligands;Encyclopedia of Cell Biology;2023

3. Unexpected structures formed by the kinase RET C634R mutant extracellular domain suggest potential oncogenic mechanisms in MEN2A;Journal of Biological Chemistry;2022-10

4. Missense Variants in GFRA1 and NPNT Are Associated with Congenital Anomalies of the Kidney and Urinary Tract;Genes;2022-09-21

5. Cryo-electron Microscopic Analysis of Single-Pass Transmembrane Receptors;Chemical Reviews;2022-06-17