c-Src Binds to the Cancer Drug Imatinib with an Inactive Abl/c-Kit Conformation and a Distributed Thermodynamic Penalty
Author:
Publisher
Elsevier BV
Subject
Molecular Biology,Structural Biology
Reference42 articles.
1. A novel mode of Gleevec binding is revealed by the structure of spleen tyrosine kinase;Atwell;J. Biol. Chem.,2004
2. Mechanisms of autoinhibition and STI-571/imatinib resistance revealed by mutagenesis of BCR-ABL;Azam;Cell,2003
3. Characterization of pp60c-src tyrosine kinase activities using a continuous assay: autoactivation of the enzyme is an intermolecular autophosphorylation process;Barker;Biochemistry,1995
4. Tyrosine phosphate hydrolysis of host proteins by an essential Yersinia virulence determinant;Bliska;Proc. Natl. Acad. Sci. USA,1991
5. Crystallography & NMR system: a new software suite for macromolecular structure determination;Brunger;Acta Crystallogr. D Biol. Crystallogr.,1998
Cited by 204 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Elucidating molecular mechanism and chemical space of chalcones through biological networks and machine learning approaches;Computational and Structural Biotechnology Journal;2024-12
2. The conformation of the nSrc specificity-determining loops in the Src and Abl SH3 domains are modulated by a “WX” conserved sequence motif;2024-08-26
3. Practical Perspectives and Roles of XRD in Drug Discovery: A Review;Current Analytical Chemistry;2024-08
4. A comprehensive exploration of the druggable conformational space of protein kinases using AI-predicted structures;PLOS Computational Biology;2024-07-24
5. Bidirectional path-based non-equilibrium simulations for binding free energy;Molecular Physics;2024-07-08
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3