Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain-Reference-Cited by-同舟云学术

Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain

Published:2021-11 Issue:11 Volume:29 Page:1241-1252.e5
ISSN:0969-2126
Container-title:Structure
language:en
Short-container-title:Structure

Author:

Szykowska Aleksandra,Chen Yu^ORCID,Smith Thomas B.^ORCID,Preger Charlotta,Yang Jingjing,Qian Dongming,Mukhopadhyay Shubhashish M.^ORCID,Wigren Edvard^ORCID,Neame Stephen J.,Gräslund Susanne,Persson Helena,Atkinson Peter J.,Di Daniel Elena^ORCID,Mead Emma,Wang John,Davis John B.,Burgess-Brown Nicola A.,Bullock Alex N.^ORCID

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference60 articles.

1. A time- and cost-efficient system for high-level protein production in mammalian cells;Aricescu;Acta Crystallogr. D. Biol. Crystallogr.,2006

2. Meprin β cleaves TREM2 and controls its phagocytic activity on macrophages;Berner;FASEB J.,2020

3. Microglia-mediated neurotoxicity: uncovering the molecular mechanisms;Block;Nat. Rev. Neurosci.,2007

4. BUSTER Version X.Y.Z. Cambridge, United Kingdom Glob;Bricogne,2016

5. TREM2-activating antibodies abrogate the negative pleiotropic effects of the Alzheimer’s disease variant Trem2R47Hon murine myeloid cell function;Cheng;J. Biol. Chem.,2018

Cited by 11 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Microglia and TREM2;Neuropharmacology;2024-10

2. Multimerization of TREM2 is impaired by Alzheimer's disease–associated variants;Alzheimer's & Dementia;2024-07-20

3. Decoding sTREM2: its impact on Alzheimer’s disease – a comprehensive review of mechanisms and implications;Frontiers in Aging Neuroscience;2024-06-07

4. Artificial intelligence for drug discovery and development in Alzheimer's disease;Current Opinion in Structural Biology;2024-04

5. sTREM2 in the prognostic evaluation of acute lung injury after cardiac surgery in infants;Pediatric Research;2023-11-25