Hydrophobic Sliding: A Possible Mechanism for Drug Resistance in Human Immunodeficiency Virus Type 1 Protease
Author:
Publisher
Elsevier BV
Subject
Molecular Biology,Structural Biology
Reference42 articles.
1. Drug resistance of HIV-1 protease against JE-2147: I47V mutation investigated by molecular dynamics simulation;Bandyopadhyay;Chem. Biol. Drug Des.,2006
2. Molecular dynamics with coupling to an external bath;Berendsen;J. Chem. Phys.,1984
3. The missing term in effective pair potentials;Berendsen;J. Phys. Chem.,1987
4. The Amber biomolecular simulation programs;Case;J. Comput. Chem.,2005
5. Mutagenesis of the dimer interface residues of tethered and untethered HIV-1 protease result in differential activity and suggest multiple mechanisms of compensation;Choudhury;Virology,2003
Cited by 74 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Natural Polymorphisms D60E and I62V Stabilize a Closed Conformation in HIV-1 Protease in the Absence of an Inhibitor or Substrate;Viruses;2024-02-02
2. HIV Protease Hinge Region Insertions at Codon 38 Affect Enzyme Kinetics, Conformational Stability and Dynamics;The Protein Journal;2023-07-08
3. Selection of HIV-1 for resistance to fifth-generation protease inhibitors reveals two independent pathways to high-level resistance;eLife;2023-03-15
4. HIV and Drug-Resistant Subtypes;Microorganisms;2023-01-15
5. Non-active site mutations in the HIV protease: Diminished drug binding affinity is achieved through modulating the hydrophobic sliding mechanism;International Journal of Biological Macromolecules;2022-09
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3