Combined overexpression of ATXN1L and mutant ATXN1 knockdown by AAV rescue motor phenotypes and gene signatures in SCA1 mice
Author:
Funder
National Ataxia Foundation
NINDS
Publisher
Elsevier BV
Subject
Genetics,Molecular Biology,Molecular Medicine
Reference41 articles.
1. Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1;Lim;Nature,2008
2. Partial loss of ataxin-1 function contributes to transcriptional dysregulation in spinocerebellar ataxia type 1 pathogenesis;Crespo-Barreto;PLoS Genet.,2010
3. Nuclear inclusions in spinocerebellar ataxia type 1;Duyckaerts;Acta Neuropathol.,1999
4. Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures;Skinner;Nature,1997
5. SCA1 transgenic mice: a model for neurodegeneration caused by an expanded CAG trinucleotide repeat;Burright;Cell,1995
Cited by 9 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Cas9 editing of ATXN1 in a spinocerebellar ataxia type 1 mice and human iPSC-derived neurons;Molecular Therapy - Nucleic Acids;2024-12
2. Molecular therapy for polyQ disorders: from bench to clinical trials;Trends in Molecular Medicine;2024-09
3. Spinocerebellar ataxias: from pathogenesis to recent therapeutic advances;Frontiers in Neuroscience;2024-06-04
4. Polyglutamine disorders: Pathogenesis and potential drug interventions;Life Sciences;2024-05
5. Precise editing of pathogenic nucleotide repeat expansions in iPSCs using paired prime editor;Nucleic Acids Research;2024-04-25
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3