Point Mutations in Retargeted gD Eliminate the Sensitivity of EGFR/EGFRvIII-Targeted HSV to Key Neutralizing Antibodies-Reference-Cited by-同舟云学术

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Point Mutations in Retargeted gD Eliminate the Sensitivity of EGFR/EGFRvIII-Targeted HSV to Key Neutralizing Antibodies

Published:2020-03 Issue: Volume:16 Page:145-154
ISSN:2329-0501
Container-title:Molecular Therapy - Methods & Clinical Development
language:en
Short-container-title:Molecular Therapy - Methods & Clinical Development

Author:

Tuzmen Ceren,Cairns Tina M.,Atanasiu Doina,Lou Huan,Saw Wan Ting,Hall Bonnie L.,Cohen Justus B.,Cohen Gary H.,Glorioso Joseph C.

Funder

CTSA SPIRiT Consortium

ACGT

2018 Investigator’s Award in Cell and Gene Therapy for Cancer Research

NIH

Publisher

Elsevier BV

Subject

Genetics,Molecular Biology,Molecular Medicine

Reference37 articles.

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2. First oncolytic virus approved for melanoma immunotherapy;Pol;OncoImmunology,2015

3. Regulation of herpes simplex virus glycoprotein-induced cascade of events governing cell-cell fusion;Atanasiu;J. Virol.,2016

4. The fusion loops of the initial prefusion conformation of herpes simplex virus 1 fusion protein point toward the membrane;Fontana;MBio,2017

5. Effective treatment of an orthotopic xenograft model of human glioblastoma using an EGFR-retargeted oncolytic herpes simplex virus;Uchida;Mol. Ther.,2013

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1. Oncolytic herpes simplex viruses designed for targeted treatment of EGFR-bearing tumors;Molecular Therapy: Oncology;2024-03

2. Promoting Oncolytic Vector Replication with Switches that Detect Ubiquitous Mutations;Current Cancer Therapy Reviews;2024-01

3. Novel mutations in UL24 and gH rescue efficient infection of an HSV vector retargeted to TrkA;Molecular Therapy - Methods & Clinical Development;2023-09

4. Preexisting immunity: Barrier or bridge to effective oncolytic virus therapy?;Cytokine & Growth Factor Reviews;2023-04

5. Modelling the spatial dynamics of oncolytic virotherapy in the presence of virus-resistant tumour cells;PLOS Computational Biology;2022-12-06

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