Chronic 2-Fold Elevation of Endogenous GDNF Levels Is Safe and Enhances Motor and Dopaminergic Function in Aged Mice-Reference-Cited by-同舟云学术

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Chronic 2-Fold Elevation of Endogenous GDNF Levels Is Safe and Enhances Motor and Dopaminergic Function in Aged Mice

Published:2020-06 Issue: Volume:17 Page:831-842
ISSN:2329-0501
Container-title:Molecular Therapy - Methods & Clinical Development
language:en
Short-container-title:Molecular Therapy - Methods & Clinical Development

Author:

Turconi Giorgio,Kopra Jaakko,Võikar Vootele,Kulesskaya Natalia,Vilenius Carolina,Piepponen T. Petteri,Andressoo Jaan-Olle

Funder

Finnish Parkinson Foundation

Academy of Finland

Sigrid Jusélius Foundation

Faculty of Medicine at the University of Helsinki

Helsinki Institute of Life Science

European Research Council

Alzheimerfonden

Publisher

Elsevier BV

Subject

Genetics,Molecular Biology,Molecular Medicine

Reference59 articles.

1. GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons;Lin;Science,1993

2. Glial cell line-derived neurotrophic factor reverses toxin-induced injury to midbrain dopaminergic neurons in vivo;Hoffer;Neurosci. Lett.,1994

3. Randomized trial of intermittent intraputamenal glial cell line-derived neurotrophic factor in Parkinson’s disease;Whone;Brain,2019

4. Extended Treatment with Glial Cell Line-Derived Neurotrophic Factor in Parkinson’s Disease;Whone;J. Parkinsons Dis.,2019

5. Trial of magnetic resonance-guided putaminal gene therapy for advanced Parkinson’s disease;Heiss;Mov. Disord.,2019

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1. Motor learning is regulated by GDNF levels in postnatal cerebellar Purkinje cells;2024-09-06

2. Neurotrophic Factors in Parkinson’s Disease: Clinical Trials;Stem Cell Biology and Regenerative Medicine;2024

3. Oxidative stress induced by sustained supraphysiological intrastriatal GDNF delivery is prevented by dose regulation;Molecular Therapy - Methods & Clinical Development;2023-12

4. Finding an Optimal Level of GDNF Overexpression: Insights from Dopamine Cycling;Cellular and Molecular Neurobiology;2023-07-06

5. Increased Physiological GDNF Levels Have No Effect on Dopamine Neuron Protection and Restoration in a Proteasome Inhibition Mouse Model of Parkinson’s Disease;eneuro;2023-01-23

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