Prevalence of Pre-existing Antibodies to CRISPR-Associated Nuclease Cas9 in the USA Population-Reference-Cited by-同舟云学术

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Prevalence of Pre-existing Antibodies to CRISPR-Associated Nuclease Cas9 in the USA Population

Published:2018-09 Issue: Volume:10 Page:105-112
ISSN:2329-0501
Container-title:Molecular Therapy - Methods & Clinical Development
language:en
Short-container-title:Molecular Therapy - Methods & Clinical Development

Author:

Simhadri Vijaya L.,McGill Joseph,McMahon Shane,Wang Junxia,Jiang Haiyan,Sauna Zuben E.

Funder

U.S. Food and Drug Administration

Publisher

Elsevier BV

Subject

Genetics,Molecular Biology,Molecular Medicine

Reference25 articles.

1. Development and applications of CRISPR-Cas9 for genome engineering;Hsu;Cell,2014

2. The CRISPR/Cas9 system: Their delivery, in vivo and ex vivo applications and clinical development by startups;Song;Biotechnol. Prog.,2017

3. Identification of pre-existing adaptive immunity to Cas9 proteins in humans;Charlesworth;bioRxiv,2018

4. T-cell dependent immunogenicity of protein therapeutics: Preclinical assessment and mitigation;Jawa;Clin. Immunol.,2013

5. Immunogenicity of therapeutic recombinant immunotoxins;Mazor;Immunol. Rev.,2016

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