Codon-Optimization of Wild-Type Adeno-Associated Virus Capsid Sequences Enhances DNA Family Shuffling while Conserving Functionality-Reference-Cited by-同舟云学术

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Codon-Optimization of Wild-Type Adeno-Associated Virus Capsid Sequences Enhances DNA Family Shuffling while Conserving Functionality

Published:2019-03 Issue: Volume:12 Page:71-84
ISSN:2329-0501
Container-title:Molecular Therapy - Methods & Clinical Development
language:en
Short-container-title:Molecular Therapy - Methods & Clinical Development

Author:

Cabanes-Creus Marti,Ginn Samantha L.,Amaya Anais K.,Liao Sophia H.Y.,Westhaus Adrian,Hallwirth Claus V.,Wilmott Patrick,Ward Jason,Dilworth Kimberley L.,Santilli Giorgia,Rybicki Arkadiusz,Nakai Hiroyuki,Thrasher Adrian J.,Filip Adrian C.,Alexander Ian E.,Lisowski Leszek

Funder

CMRI Vector and Genome Engineering Facility

Australian National Health and Medical Research Council

Australian Research Council

Wellcome Trust

NIHR Great Ormond Street Hospital Biomedical Research Centre

NIH

Publisher

Elsevier BV

Subject

Genetics,Molecular Biology,Molecular Medicine

Reference59 articles.

1. Lessons learned from the clinical development and market authorization of Glybera;Bryant;Hum. Gene Ther. Clin. Dev.,2013

2. Endgame: glybera finally recommended for approval as the first gene therapy drug in the European union;Ylä-Herttuala;Mol. Ther.,2012

3. (2018). FDA approves hereditary blindness gene therapy. Nat. Biotechnol. 36, 6.

4. Investor outlook: rising from the Ashes; GSK’s European Approval of Strimvelis for ADA-SCID;Schimmer;Hum. Gene Ther. Clin. Dev.,2016

5. Adeno-associated virus serotypes for gene therapeutics;Lisowski;Curr. Opin. Pharmacol.,2015

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