Monitoring cell-mediated immune responses in AAV gene therapy clinical trials using a validated IFN-γ ELISpot method-Reference-Cited by-同舟云学术

Monitoring cell-mediated immune responses in AAV gene therapy clinical trials using a validated IFN-γ ELISpot method

Published:2021-09 Issue: Volume:22 Page:183-195
ISSN:2329-0501
Container-title:Molecular Therapy - Methods & Clinical Development
language:en
Short-container-title:Molecular Therapy - Methods & Clinical Development

Author:

Patton Kathryn S.,Harrison M. Travis,Long Brian R.,Lau Kelly,Holcomb Jennifer,Owen Rachel,Kasprzyk Theresa,Janetzki Sylvia,Zoog Stephen J.,Vettermann Christian

Funder

BioMarin Pharmaceutical

Publisher

Elsevier BV

Subject

Genetics,Molecular Biology,Molecular Medicine

Reference51 articles.

1. Long-term safety and efficacy of factor IX gene therapy in hemophilia B;Nathwani;N. Engl. J. Med.,2014

2. Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response;Manno;Nat. Med.,2006

3. Basic biology of adeno-associated virus (AAV) vectors used in gene therapy;Balakrishnan;Curr. Gene Ther.,2014

4. Improvements in gene therapy: averting the immune response to adenoviral vectors;Ritter;BioDrugs,2002

5. Emerging Issues in AAV-Mediated In Vivo Gene Therapy;Colella;Mol. Ther. Methods Clin. Dev.,2017

Cited by 17 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The evolving landscape of gene therapy for congenital severe hemophilia: a 2024 state of the art;Bleeding, Thrombosis and Vascular Biology;2024-09-04

2. Clinical immunogenicity outcomes from GENEr8-1, a phase 3 study of valoctocogene roxaparvovec, an AAV5-vectored gene therapy for hemophilia A;Molecular Therapy;2024-07

3. Development of an Enzyme-Linked Immunosorbent Spot Assay for the Assessment of Adeno-Associated Virus Peptides to Examine Immune Safety;Human Gene Therapy;2024-07-01

4. The menace of severe adverse events and deaths associated with viral gene therapy and its potential solution;Medicinal Research Reviews;2024-03-28

5. Clinical Pharmacology Perspective on Development of Adeno‐Associated Virus Vector‐Based Retina Gene Therapy;Clinical Pharmacology & Therapeutics;2024-03-07