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NFAT-Specific Inhibition by dNP2-VIVIT Ameliorates Autoimmune Encephalomyelitis by Regulation of Th1 and Th17

  • Published:2020-03 Issue: Volume:16 Page:32-41
  • ISSN:2329-0501
  • Container-title:Molecular Therapy - Methods & Clinical Development
  • language:en
  • Short-container-title:Molecular Therapy - Methods & Clinical Development

Author:

Lee Hong-Gyun,Kim Li-Kyung,Choi Je-Min

Funder

Bio & Medical Technology Development Program

Basic Science Research Program

National Research Foundation

Korean Government

Publisher

Elsevier BV

Subject

Genetics,Molecular Biology,Molecular Medicine

Reference58 articles.

1. Identification of a putative regulator of early T cell activation genes;Shaw;Science,1988

2. Signal integration by transcription-factor assemblies: interactions of NF-AT1 and AP-1 on the IL-2 promoter;Chen;Cold Spring Harb. Symp. Quant. Biol.,1999

3. Comparison of the effects of FK-506, cyclosporin A and rapamycin on IL-2 production;Henderson;Immunology,1991

4. NFAT proteins: key regulators of T-cell development and function;Macian;Nat. Rev. Immunol.,2005

5. Molecular basis of calcium signaling in lymphocytes: STIM and ORAI;Hogan;Annu. Rev. Immunol.,2010

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