The degradation of N,N′,N′′-triethylenephosphoramide in aqueous solutions: a qualitative and kinetic study

Author:

van Maanen Rianne J.,Tijhof Inge M.,Damen J.Mirjam A.,Zwikker Jan W.,Beijnen Jos H.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference20 articles.

1. Acid-catalyzed conversion of triethyleneimine thiophosphoramide (thio-TEPA) to an SH compound;Benckhuijsen;Biochem. Pharmacol.,1968

2. Uber einige reaktionen des Aethylen-imins;Bestian;Justus Liebig’s annln chemie,1950

3. Modulation of thioTEPA anti-tumor-activity in-vivo by alteration of liver cytochrome P450-catalyzed drug-metabolism;Chang;J. Pharmacol. Exp. Ther.,1995

4. Human plasma pharmacokinetics and urinary excretion of thioTEPA and its metabolites;Cohen;Cancer Treat. Rep.,1986

5. Effects of pH and temperature on the stability and decomposition of N,N′,N′′-triethylenethiophosphoramide in urine and buffer;Cohen;Cancer Res.,1984

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