Lymphatic uptake of MK-386, a sterol 5α-reductase inhibitor, from aqueous and lipid formulations

Author:

Kwei Gloria Y,Novak Linda B,Hettrick Lisa H,Reiss Elisabeth R,Fong Eva K,Olah Timothy V,Loper Alice E

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference12 articles.

1. Improved oral bioavailability of propranolol in healthy human volunteers using a liver bypass drug delivery system containing oleic acid;Barnwell;Int. J. Pharm.,1992

2. Estimating the maximal potential for intestinal lymphatic transport of lipophilic drug molecules;Charman;Int. J. Pharm.,1986

3. Targeting of drugs to the lymph;De Nijs;Acta Pharm. Technol.,1987

4. Factors regulating the exchange of nutrients and drugs between lymph and blood in the small intestine;Deak;Microcirc. Endothel. Lymph.,1984

5. MK-386: a potent, selective inhibitor of the human type 1 5 alpha-reductase;Ellsworth;J. Steroid Biochem. Mol. Biol.,1996

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