Safety Profile, Pharmacokinetics, and Pharmacodynamics of Siplizumab, A Humanized Anti-CD2 Monoclonal Antibody, in Renal Allograft Recipients

Author:

Pruett T.L.,McGory R.W.,Wright F.H.,Pescovitz M.D.,Yang H.,McClain J.B.

Publisher

Elsevier BV

Subject

Transplantation,Surgery

Reference10 articles.

1. An anti-CD2 mAb induces immunosuppression and hyporesponsiveness of CD2+ human T cells in vitro;Latinne;Int Immunol,1996

2. The biology of CD2: adhesion, transmembrane signal, and regulatory receptor of immunity;Bromberg;J Surg Res,1993

3. Blockade of multiple costimulatory receptors induces hyporesponsiveness: inhibition of CD2 plus CD28 pathways;Woodward;Transplantation,1996

4. Facilitators and barriers to adherence with home monitoring using electronic spirometry;de la Parra;Inhibition of T cell activation by LO CD2 a, a rat monoclonal antibody against the human CD2 glycoprotein,1991

5. BTI-322 for induction therapy after renal transplantation: a randomized study;Squifflet;Transplant Proc,1997

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