Secondary endpoints cannot be validly analyzed if the primary endpoint does not demonstrate clear statistical significance
Author:
Publisher
Elsevier BV
Subject
Pharmacology
Reference5 articles.
1. Note for guidance: biostatistical methodology in clinical trials in applications for marketing authorization for medical products;CPMP Working Party and Efficacy of Medicinal Products;Stat Med,1995
2. Testing the hypothesis that matters for multiple primary endpoints;Capizzi;Drug Info J,1996
3. Sample sizes for constructing confidence intervals and testing hypotheses;Bristol;Stat Med,1989
4. The behavior of the p-value when the alternative hypothesis is true;Hung;Biometrics,1997
5. A comment on replication, p-values and evidence;Goodman;Stat Med,1992
Cited by 105 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Over-the-scope clip as first-line treatment of peptic ulcer bleeding: a multicenter randomized controlled trial (TOP Study);Endoscopy;2024-04-10
2. Editorial Commentary: Knee Lateral Extra-articular Tenodesis Procedures: Appropriate Study Design Is Essential for Reducing Conflicting Findings and Unnecessary Controversy in the Orthopaedic Literature;Arthroscopy: The Journal of Arthroscopic & Related Surgery;2024-03
3. (Re)animation of a stuffed plush bunny;European Journal of Anaesthesiology;2023-11-08
4. Influence of daily usage times on patients’ compliance during at-home bleaching: a randomized clinical trial;Journal of Applied Oral Science;2023
5. A randomized, sham-controlled, quintuple-blinded trial to evaluate the NET device as an alternative to medication for promoting opioid abstinence;Contemporary Clinical Trials Communications;2022-12
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3