Design and fabrication of an integrated 3D dynamic multicellular liver-on-a-chip and its application in hepatotoxicity screening

Author:

Zheng Yi-boORCID,Ma Li-dong,Wu Jian-lin,Wang Yi-ming,Meng Xian-sheng,Hu Ping,Liang Qiong-lin,Xie Yuan-yuan,Luo Guo-an

Funder

National Key Research and Development Program of China

Ministry of Science and Technology of the People's Republic of China

Science and Technology Development Fund

Fundo para o Desenvolvimento das Ciências e da Tecnologia

Publisher

Elsevier BV

Subject

Analytical Chemistry

Reference37 articles.

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3. Role of biotransformation in drug-induced toxicity: influence of intra- and inter-species differences in drug metabolism;Baillie;Drug Metabol. Pharmacokinet.,2011

4. In vitro platforms for evaluating liver toxicity;Bale;Exp. Biol. Med.,2014

5. Species differences in the pharmacokinetics and metabolism of indinavir, a potent human immunodeficiency virus protease inhibitor;Lin;Drug Metab. Dispos.,1996

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