Identification of S-(2,5-dihydroxyphenyl)-cysteine and S-(2,5-dihydroxyphenyl)-N-acetyl-cysteine as urinary metabolites of acetaminophen in the mouse. Evidence for p-benzoquinone as a reactive intermediate in acetaminophen metabolism-Reference-Cited by-同舟云学术

Identification of S-(2,5-dihydroxyphenyl)-cysteine and S-(2,5-dihydroxyphenyl)-N-acetyl-cysteine as urinary metabolites of acetaminophen in the mouse. Evidence for p-benzoquinone as a reactive intermediate in acetaminophen metabolism

Published:1988 Issue:1-2 Volume:68 Page:85-98
ISSN:0009-2797
Container-title:Chemico-Biological Interactions
language:en
Short-container-title:Chemico-Biological Interactions

Author:

Pascoe Gary A.,Calleman Carl Johan,Baille Thomas A.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference24 articles.

1. Acetaminophen-induced hepatic necrosis. IV. Protective role of glutathione;Mitchell;J. Pharmacol. Exp. Ther.,1973

2. Evidence for the involvement of N-acetyl-p-benzoquinone imine in acetaminophen metabolism;Miner;Biochem. Pharmacol.,1979

3. Evidence that acetaminophen and N-hydroxyacetaminophen form a common arylating intermediate, N-acetyl-p-benzoquinone imine;Corcoran;Mol. Pharmacol.,1980

4. Peroxidase-mediated formation of reactive metabolites of acetaminophen;Nelson;Mol. Pharmacol.,1981

5. Acetaminophen-induced hepatotoxicity;Hinson;Life Sci.,1981

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