Structural requirements for substrates of cytochromes P-450 and P-448

Author:

Lewis David F.V.,Ioannides Costas,Parke Dennis V.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference56 articles.

1. Microsomal enzymes and toxicity — conclusions;Parke,1985

2. Molecular dimensions of the substrate binding site of cytochrome P-448;Lewis;Biochem. Pharmacol.,1986

3. Structure-activity models for toxicity testing;Parke;Fed. Eur. Soc. Toxicol.,1986

4. Cytochrome P-450 induction by clofibrate. Purification and properties of a hepatic cytochrome P-450 relatively specific for the 12-hydroxylation and 11-hydroxylation of dodecanoic acid;Gibson;Biochem. J.,1982

5. The cytochromes P-448 — A unique family of enzymes involved in chemical toxicity and carcinogenicity;Ioannides;Biochem. Pharmacol.,1987

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