Pulegone mediated hepatotoxicity: Evidence for covalent binding of R(+)-[14C]pulegone to microsomal proteins in vitro

Author:

Madyastha K.M.,Moorthy B.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference17 articles.

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2. clinical toxicology of commercial products;Gleason,1969

3. Hapatotoxicity and pulmonary toxicity of pennyroyal oil and its constituent terpenes in the mouse;Gordon;Toxicol. Appl. Pharmacol.,1982

4. In vivo and in vitro destruction of rat liver cytochrome P-450 by a monoterpene ketone, pulegone;Madyastha;Biochem. Biophys. Res. Commun.,1985

5. Metabolism of a monoterpene ketone, R-(+)-pulegone — a hepatotoxin in rats;Moorthy;Xenobiotica,1989

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