Metabolic and mutagenicity studies on DDT and 15 derivatives. Detection of 1.1-bis(p-chlorophenyl)-2,2-dichloroethane and 1.1-bis(p-chlorophenyl)-2,2,2-trichloroethyl acetate (kelthane acetate) as mutagens in Salmonella typhimurium and of 1.1-bis(p-chlorophenyl) ethylene oxide, a likely metabolite, as an alkylating agent

Author:

Planche G.,Croisy A.,Malaveille C.,Tomatis L.,Bartsch H.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference50 articles.

1. Metabolic products of p,p′-DDT in the rat;Peterson;Toxicol. Appl. Pharmacol.,1964

2. In vivo detoxification ofp,p′-DDT via p,p′-DDE to p,p′-DDA in rats;Datta;Ind. Med.,1970

3. p.p′-DDT detoxification by isolated perfused rat liver and kidney;Datta;Ind. Med.,1970

4. Metabolism of 14C-DDT in the mouse and hamster;Gingell;Xenobiotica,1976

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