The formation of 6,7-dihydro-7-hydroxy-1-hydroxymethyl-5H-pyrrolizine, a metabolite of pyrrolizidine alkaloids-Reference-Cited by-同舟云学术

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The formation of 6,7-dihydro-7-hydroxy-1-hydroxymethyl-5H-pyrrolizine, a metabolite of pyrrolizidine alkaloids

Published:1986-02 Issue:2 Volume:57 Page:217-222
ISSN:0009-2797
Container-title:Chemico-Biological Interactions
language:en
Short-container-title:Chemico-Biological Interactions

Author:

Kedzierski Bogdan,Buhler Donald R.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference13 articles.

1. Toxicity and metabolism of Senecio alkaloids;Mattocks,1972

2. Hepatotoxic Pyrrolizidine Alkaloids;Peterson,1983

3. Acute hepatotoxicity and pyrrolic metabolites in rats dosed with pyrrolizidine alkaloids;Mattocks;Chem.-Biol. Interact.,1972

4. Carcinogenic plant products and DNA;Culvenor,1979

5. Metabolic conversion of heliotridine-based pyrrolizidine alkaloids to dehydroheliotridine;Jago;Mol. Pharmacol.,1970

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1. Traditional uses, phytochemistry, pharmacology, toxicity and clinical application of traditional Chinese medicine Cynoglossum amabile: a review;Frontiers in Pharmacology;2024-04-09

2. Synthesis Studies of Pyrrolizidine Derivatives;Journal of Organic Chemistry Research;2024

3. Hepatotoxicity and Tumorigenicity Induced by Metabolic Activation of Pyrrolizidine Alkaloids in Herbs;Current Drug Metabolism;2011-11-01

4. Formation of DHP-derived DNA adducts from metabolic activation of the prototype heliotridine-type pyrrolizidine alkaloid, heliotrine;Toxicology Letters;2008-05

5. Pyrrolizidine Alkaloids—Genotoxicity, Metabolism Enzymes, Metabolic Activation, and Mechanisms;Drug Metabolism Reviews;2004-01

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