The mechanism of alkylation of DNA by 5-(3-methyl-l-triazeno) imidazole-4-carboxamide (MIC), a metabolite of dic (NSC-45388) non-involvement of diazomethane

Author:

Nagasawa H.T.,Shirota F.N.,Mizuno N.S.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference34 articles.

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2. Antitumor activity of triazenoimidazoles;Shealy;Biochem. Pharmacol.,1963

3. Further investigation on the carcinostatic activity of 4(or 5)-aminoimidazole-5(or 4)-carboxamide derivatives: structure-activity relationship;Hano;Gann,1968

4. Antitumor activity of 4(or 5)-aminoimidazole-5(or 4)-carboxamide derivatives;Horii;Gann,1965

5. 5-(3,3-Dimethyl-1-triazeno)imidazole-4-carboxamide (DTIC, DIC, NSC-45388)—a new antitumor agent with activity against malignant melanoma;Carter;European J. Cancer,1972

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3. Noninvasive Methods for Measuring DNA Alkylation in Experimental Animals and Humans;Environmental Health Perspectives;1993-10

4. Noninvasive methods for measuring DNA alkylation in experimental animals and humans.;Environmental Health Perspectives;1993-10

5. Mechanisms of the Biological Actions of Triazenes;Triazenes;1990

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