2-Chlorodeoxyadenosine inhibits the repair of DNA double-strand breaks and does not inhibit the repair of DNA single-strand breaks in X-irradiated Chinese hamster V79 cells

Author:

Kuwabara M.,Tanabe K.,Hiraoka W.,Tamura Y.,Sato F.,Matsuda A.,Ueda T.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference30 articles.

1. Antileukemic and immunosuppressive activity of 2-chlorodeoxyadenosine;Carson,1984

2. Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to non-dividing human lymphocytes;Seto;J. Clin. Invest.,1985

3. Inhibition of DNA repair by deoxyadenosine in resting human lymphocytes;Seto;J. Immunol.,1986

4. Effects of cytotoxicity of 2-chloro-2′-deoxyadenosine on cell growth, clonogenicity, DNA synthesis and cell cycle kinetics;Huang;Cancer Res.,1986

5. Interaction of 2-halogenated dATP analogs (F, Cl and Br) with human DNA polymerases, DNA primase and ribonucleotide reductase;Parker;Mol. Pharmacol.,1988

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