Cytochrome P450 enzymes involved in the enhancement of propranolol N-desisopropylation after repeated administration of propranolol in rats

Author:

Narimatsu Shizuo,Mochida Masayuki,Matsumoto Takahiro,Masubuchi Yasuhiro,Horie Toshiharu,Nagata Kiyoshi,Funae Yoshihiko,Cho Arthur K.,Suzuki Tokuji

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference41 articles.

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2. Clinical pharmacology of propranolol;Nies;Circulation,1975

3. Quantitative account of propranolol metabolism in urine of normal man;Walle;Drug Metab. Dispos.,1985

4. New ring-hydroxylated metabolites of propranolol. Species differences and stereospecific 7-hydroxylation;Walle;Drug Metab. Dispos.,1982

5. quantitative metabolic fate of propranolol in the dog, rat, and hamster using radiotracer, high performance liquid chromatography, and gas chromatography-mass spectrometry techniques;Bargar;Drug Metab. Dispos.,1983

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