Absolute stereochemistry of the trans-dihydrodiols formed from benzo[a]anthracene by liver microsomes

Author:

Thakker D.R.,Levin W.,Yagi H.,Turujman S.,Kapadia D.,Conney A.H.,Jerina D.M.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference37 articles.

1. Metabolic conversion of benzo[a]pyrene by Syrian hamster liver microsomes and binding of metabolites to deoxyribonucleic acid;Borgen;J. Med. Chem.,1973

2. Metabolic activation of benzo[a]pyrene by a diol epoxide;Sims;Nature,1974

3. Tumorigenicity Studies with diol-epoxides of benzo[a]pyrene which indicate that (±)-7β,8α-dihydroxy-9α,10α-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene is an ultimate carcinogen in newborn mice;Kapitulnik;Cancer Res.,1978

4. Oxidation at Carbon;Jerina,1976

5. Mutagenicity of benzo[a]pyrene derivatives and the description of a quantum mechanical model which predicts the ease of carbonium ion formation from diol epoxides;Jerina,1976

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