A molecular basis for the synergy between 17‑allylamino‑17‑demethoxy geldanamycin with Capecitabine and Irinotecan in human colorectal cancer cells through VEFG and MMP-9 gene expression

Author:

Zeynali-Moghaddam Shima,Mohammadian Mahshid,Kheradmand Fatemeh,Fathi-Azarbayjani Anahita,Rasmi Yousef,Esna-Ashari Omid,Malekinejad Hassan

Funder

Urmia University of Medical Sciences

Publisher

Elsevier BV

Subject

Genetics,General Medicine

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3. Carvacryl acetate, a novel semisynthetic monoterpene ester, binds to the TRPA 1 receptor and is effective in attenuating irinotecan-induced intestinal mucositis in mice;Alvarenga;J. Pharm. Pharmacol.,2017

4. A phase 1 dose-escalation study of irinotecan in combination with 17-allylamino-17-demethoxygeldanamycin in patients with solid tumors;Archie;Clin. Cancer Res.,2008

5. Impressive suppression of colon cancer growth by triple combination SN38/EF24/melatonin: “oncogenic” versus “onco-suppressive” reactive oxygen species;Bakalova;Anticancer Res.,2017

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