Glutamate synthase: A case-study for in silico drug screening on a complex iron–sulfur flavoenzyme?
Author:
Publisher
Elsevier BV
Subject
Genetics,General Medicine
Reference18 articles.
1. The unexpected structural role of glutamate synthase [4Fe–4S](+1,+2) clusters as demonstrated by site-directed mutagenesis of conserved C residues at the N-terminus of the enzyme beta subunit;Agnelli;Arch. Biochem. Biophys.,2005
2. Cross-talk and ammonia channeling between active centers in the unexpected domain arrangement of glutamate synthase;Binda;Struct. Fold. Des.,2000
3. Targeting glutamate synthase for tuberculosis drug development;Cheung;Hong Kong Med. J.,2011
4. Molecular dynamics simulation of the interaction between the complex iron–sulfur flavoprotein glutamate synthase and its substrates;Coiro;Protein Sci.,2004
5. The subnanometer resolution structure of the glutamate synthase 1.2-MDa hexamer by cryoelectron microscopy and its oligomerization behavior in solution: functional implications;Cottevieille;J. Biol. Chem.,2008
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