Internal exposure of rats to benzidine derived from orally administered benzidine-based dyes after intestinal azo reduction

Author:

Bos R.P.,Van Der Krieken W.,Smeijsters L.,Koopman J.P.,De Jonge H.R.,Theuws J.L.G.,Henderson P.Th.

Publisher

Elsevier BV

Subject

Toxicology

Reference14 articles.

1. Carcinogenesis, Technical Report Series No. 108. 13-Week subchronic toxicity studies of direct blue 6, direct black 38, and direct brown 95 dyes;NCI;NCI-CG-TR-108,1978

2. Metabolic reduction of benzidine azo dyes to benzidine in the rhesus monkey;Rinde;J. Natl. Cancer. Inst.,1975

3. Metabolism studies of an azo dye and pigment in the hamster based on analysis of the urine for potentially carcinogenic aromatic amine metabolites;Nony;J. Anal. Toxicol.,1980

4. Mutagenicity of urinary metabolites of benzidine and benzidine-based azo dyes;Tanaka;Int. Arch. Occup. Environ. Health,1981

5. Metabolism of benzidine-based dyes and the appearance of mutagenic metabolites in urine of rats after oral or intraperitoneal administration;Bos;Toxicology,1984

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